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Triple agonist of the GLP-1, GIP, and glucagon receptors under clinical investigation for metabolic and weight regulation. Lyophilized powder, research grade.

Axion Peptides compounds are synthesised to pharmaceutical-grade specifications and verified by independent HPLC analysis prior to release.

Frequently asked questions

What is GLP-3?

GLP-3 is the catalog name for retatrutide, a synthetic 39-amino-acid peptide that acts as a triple agonist at the GLP-1, GIP, and glucagon receptors. It is the newest molecule in the incretin receptor-agonist class and is supplied strictly for research use only.

Is GLP-3 the same as retatrutide?

Yes. GLP-3 and retatrutide describe the identical molecule and amino-acid sequence. "GLP-3" reflects its place in the receptor-agonist progression (single, then dual, then triple receptor activity), while retatrutide is the international nonproprietary name.

How is GLP-3 different from tirzepatide?

GLP-3 engages three receptors (GLP-1, GIP, and glucagon), whereas tirzepatide engages two (GLP-1 and GIP). In research models the added glucagon-receptor activity of GLP-3 is associated with greater effects on energy expenditure and hepatic lipid handling.

What is GLP-3 studied for in research?

GLP-3 is used in preclinical work on triple-agonist incretin pharmacology, energy expenditure and thermogenesis, hepatic lipid metabolism, body-composition partitioning, and glucose homeostasis. Reported studies are conducted in rodent or in-vitro systems.

What does the Certificate of Analysis verify?

Every lot ships with a third-party COA confirming purity by HPLC (>=99%), identity by mass spectrometry, and lyophilized mass. The batch-specific report is available on the product page before purchase.

How should GLP-3 be stored?

Store lyophilized GLP-3 at -20 C for long-term storage and 2-8 C for short-term use. Avoid repeated freeze-thaw cycles and keep vials sealed and protected from light.

Is GLP-3 FDA approved?

No. Retatrutide remains in clinical development and is not FDA approved. Material sold here is for laboratory research use only and is not intended for diagnostic, therapeutic, or human use.